Evidence-Based Clinical Case Analysis
Author: Andrew Bland, MD, MBA, MS
Published case reports and clinical analyses from nephrology practice. Each case integrates clinical reasoning, diagnostic workup, pathophysiology, and evidence-based management with teaching points for medical students, PA students, and residents.
Diagnostic challenges in serologically quiet lupus nephritis presenting as isolated microscopic hematuria. Covers renal-limited SLE, biopsy interpretation, the concept of "renal-first" lupus, and implications for screening algorithms. A case that changed clinical practice.
49 min read
When autoimmune and infectious etiologies produce overlapping clinical pictures. Covers serologic mimicry (ANA, RF, ANCA positivity in IE), the safety-first diagnostic principle, and a systematic approach to the SLE-IE diagnostic dilemma.
17 min read
Diagnostic challenges in suspected cardiac amyloidosis initially mistaken for cirrhotic ascites. Covers the EF-cardiac index mismatch, right heart catheterization hemodynamics, restrictive physiology, free light chain interpretation, and the differential between AL and ATTR amyloidosis.
56 min read
Inpatient case of AL amyloidosis with kappa-dominant light chain deposition disease in the differential. Covers the diagnostic workup, biopsy interpretation, staging, and initial management decisions.
19 min read
Systematic approach to right heart catheterization, echocardiographic diastolic assessment, urine protein dissection, and free light chain interpretation. Integrates hemodynamic data with laboratory findings for a comprehensive teaching case.
36 min read
Clinical assessment of coliform bacteria contamination in Iowa well water with associated acute kidney injury. Covers E. coli pathotype identification, public health implications, and management of community-acquired AKI in agricultural settings.
17 min read
Comprehensive clinical reference for E. coli pathotype classification including UPEC, ETEC, EHEC/STEC, EIEC, EAEC, and DAEC. Covers virulence mechanisms, clinical syndromes, antibiotic selection, and the critical antibiotic contraindication in EHEC/STEC (HUS risk).
20 min read
Clinical comparison of elemental phosphorus content in dietary sources versus therapeutic formulations. Practical reference for hypophosphatemia treatment decisions and phosphorus restriction counseling in ESRD.
16 min read
Andrew Bland, MD, MBA, MS | Nephrology Education Series | Urine Nephrology Now
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