CRRT: Prescribe, Deliver, Reassess

Clinical Mastery · Visual teaching summary · October 3, 2026

Andrew Bland, MD, FACP, FAAP

Visual summary

Reassess kidney recovery, changing stability, and readiness for another modality or discontinuation. Continuous therapy should have an active daily purpose.

CRRT: Prescribe, Deliver, Reassess: six-panel learning summary. Full text follows below.
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Continuous support

Continuous kidney replacement offers gradual solute and fluid management, often useful in unstable patients. Clearance depends on the selected modality and delivered effluent.

Clarify the indication

Assess electrolyte emergencies, acidemia, fluid overload, uremia, and ongoing metabolic demand. Hemodynamic instability informs modality but does not define the entire prescription.

Account for the circuit

Vascular access, filter function, anticoagulation, prefilter dilution, and downtime all influence delivery. The machine setting alone is not the actual dose.

Titrate net fluid removal

Separate clearance goals from the patient's net fluid balance. Adapt removal to perfusion, vasopressors, capillary refill, congestion, and the evolving illness.

Monitor treatment losses

Follow electrolytes, phosphate, temperature, nutrition, and drug clearance. Citrate protocols require appropriate acid–base and calcium monitoring.

Plan transitions

Reassess kidney recovery, changing stability, and readiness for another modality or discontinuation. Continuous therapy should have an active daily purpose.

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