ACE Inhibitors and ARBs: Your Kidney Plan

Patient education · Visual teaching summary · October 3, 2026

Andrew Bland, MD, FACP, FAAP

Visual summary

Use the medicine with follow-up testing and an individualized sick-day plan.

ACE Inhibitors and ARBs: Your Kidney Plan. Full text follows below.
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Why they are used

These medicines lower blood pressure and can reduce protein leakage through kidney filters. They protect many people with protein in the urine and may also help the heart.

Know your medicine

ACE inhibitors include lisinopril and enalapril. ARBs include losartan and valsartan. They are usually alternatives; taking both together is generally avoided.

Book the follow-up blood test

Ask for the potassium and creatinine check when the medicine starts or the dose changes—often within 2–4 weeks, sooner for some people. A small change can be expected, but dizziness, dehydration, or a larger rise needs review.

Do not guess during illness

Call about repeated dizziness, vomiting, diarrhea, poor intake, or a persistent dry cough. Ask for written instructions about temporary holds and restarting. Do not stop a useful medicine simply because one kidney result changed.

Check interactions

Ask before using NSAID pain relievers, potassium supplements, or potassium-based salt substitutes. Discuss pregnancy plans promptly because these medicines are unsafe during pregnancy.

Face or throat swelling: call 911

Swollen lips, tongue, or throat, or trouble breathing/swallowing can be a serious reaction. Call 911 and do not take another dose while awaiting urgent medical direction. Severe weakness, fainting, or an abnormal heartbeat also needs urgent assessment.

Supporting evidence

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