Session 5 readiness quiz

Three retrieval questions: nephrotic AKI, cirrhosis and systematic BMP interpretation

Andrew Bland, MD, FACP, FAAP · October 2026

Commit to an answer before revealing the explanation. Use the section menu to navigate; each question and answer has its own link. Five-option evidence updates ask for the most defensible direction of change; discuss a justified adjacent response.

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    Three individual retrieval decisions for the opening five minutes. Allow about 45 seconds per answer, followed by a short explanation. Record the first answer before discussion. This is formative readiness practice, not a validated assessment.

    Q1A new complication of nephrotic syndrome

    A patient with membranous nephropathy and serum albumin 1.8 g/dL develops flank pain, gross hematuria and a creatinine rise from 1.3 to 2.1 mg/dL over four days. What needs urgent exclusion?

    A.

    Renal vein thrombosis — arrange appropriate imaging and same-day nephrology contact

    B.

    Normal variation — repeat creatinine at the next routine visit

    C.

    Lower-tract retention alone — an empty bladder excludes every postrenal cause

    D.

    A steroid-responsive relapse — start prednisone before reassessing the diagnosis

    · Link to this question

    Correct answer: A

    Learning point: Nephrotic syndrome increases thrombosis risk. The acute pain, hematuria and kidney-function change warrant urgent vascular evaluation while other causes of AKI are assessed. An empty bladder excludes neither ureteral obstruction nor vascular disease. Why not the others: B delays evaluation; C overinterprets a bladder scan; D prescribes before establishing the cause. Course reading: Evidence for this case

    Evidence and objective for Q1

    Back to Q1 · All answers in this case

    Q2Low urine sodium in cirrhosis

    A patient with cirrhosis and ascites has persistent AKI after appropriate correction of a documented volume deficit. Infection, obstruction and nephrotoxic exposure have been evaluated. FENa remains below 1%. What is the best interpretation?

    A.

    Low FENa proves more fluid will restore kidney function

    B.

    HRS-AKI is a concern; low FENa does not distinguish it from other causes

    C.

    Low FENa rules out any tubular injury

    D.

    The diagnosis requires an automatic additional 48-hour albumin course

    · Link to this question

    Correct answer: B

    Learning point: Sodium avidity is common in cirrhosis and is not a fluid-response test. Persistent AKI after appropriate resuscitation raises concern for hepatorenal physiology, but the assessment remains clinical and may involve more than one mechanism. Obtain hepatology/nephrology input; routine prolonged albumin administration without assessing volume can cause harm. Why not the others: A and C overinterpret FENa; D substitutes a fixed infusion interval for assessment of the patient. Course reading: Evidence for this case

    Evidence and objective for Q2

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    Q3Read the BMP before naming the disease

    An acutely unwell adult has the results below. Creatinine was 1.0 mg/dL five days earlier. Which first interpretation uses the systematic BMP read correctly?

    Test Result Reference range
    Sodium 128 mEq/L 136–145
    Potassium 6.2 mEq/L 3.5–5.0
    Chloride 96 mEq/L 98–107
    Bicarbonate 14 mEq/L 22–26
    BUN 72 mg/dL 7–20
    Creatinine 3.0 mg/dL 0.7–1.3
    Glucose 110 mg/dL 70–140 random
    Albumin 4.0 g/dL 3.5–5.0
    Calcium 9.2 mg/dL 8.6–10.2
    Magnesium 2.0 mg/dL 1.7–2.2
    Phosphorus 5.4 mg/dL 2.5–4.5

    A.

    Hyponatremia alone; the other abnormalities can wait until it is corrected

    B.

    Chronic G4 CKD because the calculated eGFR is low on today's report

    C.

    Normal anion gap because sodium minus chloride is 32

    D.

    Urgent hyperkalemia assessment, AG 18 with low bicarbonate, and stage 3 AKI by creatinine ratio

    · Link to this question

    Correct answer: D

    Learning point: Read Na → K → Cl → bicarbonate → anion gap → BUN/creatinine → glucose, then Ca/Mg/phosphorus. AG = 128 − (96 + 14) = 18; albumin is normal. Creatinine is three times a recent baseline. Obtain an ECG and urgently manage confirmed hyperkalemia according to the clinical protocol while evaluating AKI and the acid-base disorder; a blood gas and cause-directed tests complete the assessment. Why not the others: A misses an immediate hazard; B labels chronicity from an acute change; C omits bicarbonate from the calculation. Course reading: Evidence for this case

    Evidence and objective for Q3

    Back to Q3 · All answers in this case

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