2025 AHA Expanded Hypertension Guideline
13-organization guideline analysis: PREVENT calculator, retired "hypertensive urgency" terminology, primary aldosteronism universal screening, renal denervation integration, pregnancy management (CHAP trial), cerebrovascular precision protocols, and CKM syndrome framework.
Comprehensive Hypertension Management
Evidence-based HBPM and ABPM protocols, morning BP phenotypes, CV risk reduction by BP level with NNTs, ACEi vs ARB selection framework, ACEi washout for ARNI in CKD, losartan CYP2C9 and uricosuric properties, extended half-life agents, and thiazide hyponatremia risk-benefit analysis.
Psychotropic and ADHD Medications in Hypertension and CKD
Why the pressor effect tracks norepinephrine transporter blockade rather than drug class, the CYP2D6 collision between paroxetine and metoprolol, guanfacine as a two-birds prescription, bupropion's metabolite trap in dialysis, serotonin syndrome and rhabdomyolysis, and renal dosing across both drug families.