N8 — Catheter Care and Infection Bundle FRONT
Front · at the chair
When: every catheter connection, disconnection, and dressing change.
Do this
- Check first: exit site, tunnel, dressing, and the patient (fever, chills) at every session [6].
- Masks for patient and staff; the patient turns the head away and limits talking.
- Hand hygiene, gloves, and a clean field under the catheter limbs.
- Clamp before opening. Confirm both limbs are clamped before any cap comes off.
- Scrub the hub with chlorhexidine (povidone-iodine if intolerant) every time the catheter is accessed or disconnected [6].
- Aspirate 2–5 mL of blood and lock from each lumen before connecting, one lumen at a time [6]. A taurolidine/heparin lock must always be aspirated and discarded [7].
- Dressing change: alcohol-based chlorhexidine (more than 0.5%) on the skin; exit-site ointment per your unit protocol after checking catheter compatibility; change at least weekly and whenever wet or soiled [6].
- Lock: saline flush, the prescribed lock at your protocol’s volume, clamp, and a new sterile cap every time.
- Can’t reach the prescribed blood flow? That is catheter dysfunction: check position, clamps, and flush, then follow the thrombolytic protocol.
Call the nephrologist when
- Immediately: fever, rigors, hypotension, or confusion during or after dialysis. Draw two blood cultures (catheter hub and dialysis circuit) before the first antibiotic dose [6].
- Same day: pus or spreading redness at the exit site; tenderness or redness along the tunnel; the cuff is visible or the catheter looks longer.
- Before the next session: dysfunction not fixed by bedside maneuvers or one alteplase dwell.
- Monthly at rounds: the patient still has a catheter — ask what the permanent-access plan is.
Don’t
- Don’t leave a lumen open to air — clamp first, cap every time.
- Don’t infuse or flush the lock into the patient; aspirate it.
- Don’t use the catheter for blood draws or medications outside dialysis unless ordered.
- Don’t start antibiotics before cultures [6].
- Don’t use taurolidine/heparin in a patient with heparin-induced thrombocytopenia or pork allergy [7].
N8 — Catheter Care and Infection Bundle BACK
Back · why, and the evidence
Why
- Catheter patients have about 8 times the bloodstream infection rate of fistula patients (2.16 vs 0.26 per 100 patient-months) [1].
- Units that implemented the CDC bundle (chlorhexidine, audits, competency, feedback) cut access-related bloodstream infections by 54% [2].
- Chlorhexidine skin antisepsis roughly halved catheter-related bloodstream infection compared with povidone-iodine (RR 0.49) [3].
- A once-weekly alteplase lock cut catheter malfunction from 34.8% to 20.0% and bacteremia from 13.0% to 4.5% over 6 months [4].
- A taurolidine/heparin lock cut catheter-related bloodstream infection from 8.0% to 2.3% (NNT 18) in LOCK IT-100 [5,7].
Go deeper
- Mastery page: Catheter Care, Lock Solutions, and Bloodstream Infection
- All dialysis nursing reference cards
References
- Nguyen DB, et al. National Healthcare Safety Network (NHSN) Dialysis Event Surveillance Report for 2014. Clin J Am Soc Nephrol. 2017;12:1139-1146. PubMed 28663227
- Patel PR, et al. Bloodstream infection rates in outpatient hemodialysis facilities participating in a collaborative prevention effort. Am J Kidney Dis. 2013;62:322-330. PubMed 23676763
- Chaiyakunapruk N, et al. Chlorhexidine compared with povidone-iodine solution for vascular catheter-site care: a meta-analysis. Ann Intern Med. 2002;136:792-801. PubMed 12044127
- Hemmelgarn BR, et al. Prevention of dialysis catheter malfunction with recombinant tissue plasminogen activator. N Engl J Med. 2011;364:303-312. PubMed 21268722
- Agarwal AK, et al. Taurolidine/heparin lock solution and catheter-related bloodstream infection in hemodialysis (LOCK IT-100). Clin J Am Soc Nephrol. 2023;18:1446-1455. PubMed 37678222
- Lok CE, et al. KDOQI clinical practice guideline for vascular access: 2019 update. Am J Kidney Dis. 2020;75(4 Suppl 2):S1-S164. PubMed 32778223
- DEFENCATH (taurolidine and heparin) catheter lock solution, prescribing information. CorMedix Inc.; DailyMed. dailymed.nlm.nih.gov
Reviewed by Andrew Bland, MD, FACP, FAAP · v1.0 draft 2026-09-26. For education; the physician’s written order and the unit protocol always govern.